Chemical constituents from the stems of Arfeuillea arborescens Pierre and their biological activity

Abstract

A chemical investigation of the stems of Arfeuillea arborescens Pierre, three mixtures and seven compounds were isolated from hexane, dichloromethane and ethyl acetate crude extracts. They were a mixture of long chain aliphatic hydrocarbons (C₁₈, C₂₁, C₂₅, C₃₀, C₃₂, C₃₄) a mixture of stigmasterol and β-sitosterol, a mixture of long chain aliphatic aliphatic esters, (+)-proto-quercitol, 3,5-Bis-[3,3-dimethylallyl]-p-hydroxybenzaldehyde, cyclic tris(ethylene terphthalate), stigmasteryl-3-O-β-D-glucopyranoside, scopoletin, 5-hydroxymethyl-furfuraldehyde and p-hydroxybenzoic acid. The last two compounds showed cytotoxicity against Artemia salina Linn (brine shrimp) with LC₅₀ 71.0 and 33.1 ug/ml. In addition,5-hydroxymethylfurfuraldenyde showed significant antibacterial activity against 7 microorganisms: E. coli, B. cereus, S. aureus, S. derby, E. coli 0157 : H7, L. monocytogenes and flat sour spoilage as well as antifungal activity against Cladosporium cucumerinum. This compound also showed plant growth inhibition against Oryza sativa Linn.ver. RD. 23 as well as antioxidant.